Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose?
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SUBMITTER: Foley DJ
PROVIDER: S-EPMC5113762 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
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Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose?
Foley Daniel J DJ Nelson Adam A Marsden Stephen P SP
Angewandte Chemie (International ed. in English) 20160830 44
As our understanding of the impact of specific molecular properties on applications in discovery-based disciplines improves, the extent to which published synthetic methods meet (or do not meet) desirable criteria is ever clearer. Herein, we show how the application of simple (and in many cases freely available) computational tools can be used to develop a semiquantitative understanding of the potential of new methods to support molecular discovery. This analysis can, among other things, inform ...[more]
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