Ontology highlight
ABSTRACT:
SUBMITTER: Ried JS
PROVIDER: S-EPMC5114527 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Nature communications 20161123
Large consortia have revealed hundreds of genetic loci associated with anthropometric traits, one trait at a time. We examined whether genetic variants affect body shape as a composite phenotype that is represented by a combination of anthropometric traits. We developed an approach that calculates averaged PCs (AvPCs) representing body shape derived from six anthropometric traits (body mass index, height, weight, waist and hip circumference, waist-to-hip ratio). The first four AvPCs explain >99% ...[more]