Evaluation of Lethal Giant Larvae as a Schistosomiasis Vaccine Candidate.
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ABSTRACT:
SUBMITTER: Cao Y
PROVIDER: S-EPMC5120214 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Evaluation of Lethal Giant Larvae as a Schistosomiasis Vaccine Candidate.
Cao Yufan Y Qiao Hongbin H Shi Yanli Y Han Yu Y Liu Jinming J Li Hao H Lu Ke K Lin Jiaojiao J Jin Yamei Y
BioMed research international 20161109
Schistosomiasis is a neglected tropical disease of humans, and it is considered to be the second most devastating parasitic disease after malaria. Eggs produced by normally developed female worms are important in the transmission of the parasite, and they responsible for the pathogenesis of schistosomiasis. The tumor suppressor gene <i>lethal giant larvae (lgl)</i> has an essential function in establishing apical-basal cell polarity, cell proliferation, differentiation, and tissue organization. ...[more]
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