Ontology highlight
ABSTRACT:
SUBMITTER: Ye JL
PROVIDER: S-EPMC5122420 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Ye Jin-Ling JL Gao Chun-Qi CQ Li Xiang-Guang XG Jin Cheng-Long CL Wang Dan D Shu Gang G Wang Wen-Ce WC Kong Xiang-Feng XF Yao Kang K Yan Hui-Chao HC Wang Xiu-Qi XQ
Oncotarget 20160601 25
Excitatory amino acid transporter 3 (EAAT3, encoded by SLC1A1) is an epithelial type high-affinity anionic amino acid transporter, and glutamate is the major oxidative fuel for intestinal epithelial cells. This study investigated the effects of EAAT3 on amino acid transport and cell proliferation through activation of the mammalian target of the rapamycin (mTOR) pathway in porcine jejunal epithelial cells (IPEC-J2). Anionic amino acid and cystine (Cys) transport were increased (P<0.05) by EAAT3 ...[more]