Ontology highlight
ABSTRACT:
SUBMITTER: Yu G
PROVIDER: S-EPMC5123806 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Structure (London, England : 1993) 20161101 11
The affinity cryoelectron microscopy (cryo-EM) approach has been explored in recent years to simplify and/or improve the sample preparation for cryo-EM, which can bring previously challenging specimens such as those of low abundance and/or unpurified ones within reach of the cryo-EM technique. Despite the demonstrated successes for solving structures to low to intermediate resolutions, the lack of near-atomic structures using this approach has led to a common perception of affinity cryo-EM as a ...[more]