Ontology highlight
ABSTRACT:
SUBMITTER: Ghasemi Z
PROVIDER: S-EPMC5124257 | biostudies-literature | 2016 Oct-Dec
REPOSITORIES: biostudies-literature
Ghasemi Zahra Z Hashemi Mehrdad M Ejabati Mahsa M Ebrahimi Seyyed Meisam SM Kheiri Manjili Hamidreza H Sharafi Ali A Ramazani Ali A
Avicenna journal of medical biotechnology 20161001 4
<h4>Background</h4>Genetic polymorphisms of drug metabolisms by cytochrome P450 (P450s) could affect drug response, attracting particular interest in the pharmacogenetics. Due to the importance of CYP2C19* 17 allele and its capability of super- fast metabolism and also lack of information about distribution of the alleles in Iranian population, this research aimed to use High Resolution Melting (HRM) method compared to PCR-RFLP for genotyping healthy Iranian population.<h4>Methods</h4>Blood samp ...[more]