Unknown

Dataset Information

0

Use of Coronary Ultrasound Imaging to Evaluate Ventricular Function in Adult Zebrafish.


ABSTRACT: So far, imaging of the adult zebrafish heart and assessment of heart failure in adult zebrafish have been very limited. Here, we describe a new method for in vivo imaging of the hypertrabeculated heart of the adult zebrafish using miniaturized cardiac ultrasound catheters obtained from the cardiac catheterization laboratory. This method allows the observation of the ventricle of zebrafish and the assessment of ventricular diameters during diastole and systole, as well as heart rate and fractional shortening. Significant changes in these parameters were detected through the use of an adult zebrafish heart failure model induced by chronic anemia. This imaging technique opens the door to detailed in vivo analysis of the adult heart failure phenotype in zebrafish.

SUBMITTER: Ernens I 

PROVIDER: S-EPMC5124742 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Use of Coronary Ultrasound Imaging to Evaluate Ventricular Function in Adult Zebrafish.

Ernens Isabelle I   Lumley Andrew I AI   Devaux Yvan Y   Wagner Daniel R DR  

Zebrafish 20160621 6


So far, imaging of the adult zebrafish heart and assessment of heart failure in adult zebrafish have been very limited. Here, we describe a new method for in vivo imaging of the hypertrabeculated heart of the adult zebrafish using miniaturized cardiac ultrasound catheters obtained from the cardiac catheterization laboratory. This method allows the observation of the ventricle of zebrafish and the assessment of ventricular diameters during diastole and systole, as well as heart rate and fractiona  ...[more]

Similar Datasets

| S-EPMC2292109 | biostudies-literature
| S-EPMC1951787 | biostudies-literature
| S-EPMC4091976 | biostudies-literature
| S-EPMC8367287 | biostudies-literature
| S-EPMC5613480 | biostudies-literature
| S-EPMC2581121 | biostudies-literature
| S-EPMC5784807 | biostudies-literature
| S-EPMC2791922 | biostudies-literature
| S-EPMC8489017 | biostudies-literature
| S-EPMC7077164 | biostudies-literature