Ontology highlight
ABSTRACT:
SUBMITTER: Kirkegaard H
PROVIDER: S-EPMC5127087 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Kirkegaard Hans H Pedersen Asger Roer AR Pettilä Ville V Hjort Jakob J Rasmussen Bodil Steen BS de Haas Inge I Nielsen Jørgen Feldbæk JF Ilkjær Susanne S Kaltoft Anne A Jeppesen Anni Nørgaard AN Grejs Anders Morten AM Duez Christophe Henri Valdemar CH Larsen Alf Inge AI Toome Valdo V Arus Urmet U Taccone Fabio Silvio FS Storm Christian C Laitio Timo T Skrifvars Markus B MB Søreide Eldar E
Scandinavian journal of trauma, resuscitation and emergency medicine 20161128 1
<h4>Background</h4>The TTH48 trial aims to determine whether prolonged duration (48 hours) of targeted temperature management (TTM) at 33 (±1) °C results in better neurological outcomes compared to standard duration (24 hours) after six months in comatose out-of-hospital cardiac arrest (OHCA) patients.<h4>Methods</h4>TTH48 is an investigator-initiated, multicentre, assessor-blinded, randomised, controlled superiority trial of 24 and 48 hours of TTM at 33 (±1) ° C performed in 355 comatose OHCA p ...[more]