Ontology highlight
ABSTRACT:
SUBMITTER: Carter CA
PROVIDER: S-EPMC5130044 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Carter Corey A CA Zeman Karen K Day Regina M RM Richard Patrick P Oronsky Arnold A Oronsky Neil N Lybeck Michelle M Scicinski Jan J Oronsky Bryan B
Oncotarget 20160601 26
Like Chinese boxes nesting inside each other, the classification of non-small cell lung cancer (NSCLC) is subdivided into smaller and smaller subtypes on the basis of histological and molecular attributes. The latter characterizes NSCLC by its molecular alterations and the identification of inhibitors that target these cancer-specific "driver" mutations. Despite the initial promise of precision-guided therapies to inhibit a finer and finer array of molecular subcategories, despite even the curat ...[more]