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New Synthesis of Gold- and Silver-Based Nano-Tetracycline Composites.

ABSTRACT: A new synthetic methodology of water-soluble gold and silver nanoparticles (AuNPs@TC and AgNPs@TC), using the antibiotic tetracycline (TC) as co-reducing and stabilizing agent, is reported. Both colloids exhibit high water stability. The average sizes obtained were 25±10 and 15±5?nm, respectively. Both composites were tested against TC-resistant bacteria, presenting an increasing antibacterial effect in the case of AgNPs@TC. The sensing towards metal ions was also explored. An interesting and reversible affinity of AuNPs@TC towards Al^III cations in an aqueous system was also observed.

SUBMITTER: Djafari J

PROVIDER: S-EPMC5130297 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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New Synthesis of Gold- and Silver-Based Nano-Tetracycline Composites.

Djafari Jamila J Marinho Catarina C Santos Tiago T Igrejas Gilberto G Torres Carmen C Capelo José Luis JL Poeta Patricia P Lodeiro Carlos C Fernández-Lodeiro Javier J

ChemistryOpen 20160603 3

A new synthetic methodology of water-soluble gold and silver nanoparticles (AuNPs@TC and AgNPs@TC), using the antibiotic tetracycline (TC) as co-reducing and stabilizing agent, is reported. Both colloids exhibit high water stability. The average sizes obtained were 25±10 and 15±5 nm, respectively. Both composites were tested against TC-resistant bacteria, presenting an increasing antibacterial effect in the case of AgNPs@TC. The sensing towards metal ions was also explored. An interesting and re ...[more]

PMID: 27957408

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