Ontology highlight
ABSTRACT:
SUBMITTER: Ohira T
PROVIDER: S-EPMC5132294 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Ohira Tatsuo T Sakai Kazuko K Matsubayashi Jun J Kajiwara Naohiro N Kakihana Masatoshi M Hagiwara Masaru M Hibi Masaaki M Yoshida Koichi K Maeda Junichi J Ohtani Keishi K Nagao Toshitaka T Nishio Kazuto K Ikeda Norihiko N
Cancer science 20161101 11
Next-generation sequencing (NGS) and digital PCR technologies allow analysis of the mutational profile of circulating cell-free DNA (cfDNA) in individuals with advanced lung cancer. We have now evaluated the feasibility of cfDNA sequencing for mutation detection in patients with non-small cell lung cancer at earlier stages. A total of 150 matched tumor and serum samples were collected from non-small cell lung cancer patients at stages IA-IIIA. Amplicon sequencing with DNA extracted from tumor ti ...[more]