Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez G
PROVIDER: S-EPMC5133190 | biostudies-literature | 2016 Oct - Nov
REPOSITORIES: biostudies-literature
Gonzalez Gabriel G Mehra Shyamin S Wang Ying Y Akiyama Haruhiko H Behringer Richard R RR
Differentiation; research in biological diversity 20160601 4
SOX9 is a high mobility group transcription factor that is required in many biological processes, including cartilage differentiation, endoderm progenitor maintenance, hair differentiation, and testis determination. SOX9 has also been linked to colorectal, prostate, and lung cancer. We found that SOX9 is expressed in the epithelium of the adult mouse and human uterus, predominantly marking the uterine glands. To determine if SOX9 plays a role in the development of endometrial cancer we overexpre ...[more]