Ontology highlight
ABSTRACT:
SUBMITTER: Kataoka K
PROVIDER: S-EPMC5133905 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Kataoka Kota K Ekuni Daisuke D Tomofuji Takaaki T Irie Koichiro K Kunitomo Muneyoshi M Uchida Yoko Y Fukuhara Daiki D Morita Manabu M
International journal of molecular sciences 20161116 11
The aim of this study was to investigate whether a Keap1-dependent oxidative stress detector-luciferase (OKD-LUC) mouse model would be useful for the visualization of oxidative stress induced by experimental periodontitis. A ligature was placed around the mandibular first molars for seven days to induce periodontitis. Luciferase activity was measured with an intraperitoneal injection of d-luciferin on days 0, 1, and 7. The luciferase activity in the periodontitis group was significantly greater ...[more]