Ontology highlight
ABSTRACT:
SUBMITTER: Schwartz MH
PROVIDER: S-EPMC5137444 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Schwartz Michael H MH Waldbauer Jacob R JR Zhang Lichun L Pan Tao T
Nucleic acids research 20160926 21
High translational fidelity is commonly considered a requirement for optimal cellular health and protein function. However, recent findings have shown that inducible mistranslation specifically with methionine engendered at the tRNA charging level occurs in mammalian cells, yeast and archaea, yet it was unknown whether bacteria were capable of mounting a similar response. Here, we demonstrate that Escherichia coli misacylates non-methionyl-tRNAs with methionine in response to anaerobiosis and an ...[more]