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Cytosolic delivery of large proteins using nanoparticle-stabilized nanocapsules.

ABSTRACT: We report an effective intracellular delivery strategy for proteins of high molecular weight using AuNP stabilized capsules. This strategy provides direct delivery to the cytosol, avoiding endosomal entrapment.

SUBMITTER: Tang R 

PROVIDER: S-EPMC5137506 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Cytosolic delivery of large proteins using nanoparticle-stabilized nanocapsules.

Tang Rui R   Jiang Ziwen Z   Ray Moumita M   Hou Singyuk S   Rotello Vincent M VM  

Nanoscale 20161001 42

We report an effective intracellular delivery strategy for proteins of high molecular weight using AuNP stabilized capsules. This strategy provides direct delivery to the cytosol, avoiding endosomal entrapment. ...[more]

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