Ontology highlight
ABSTRACT:
SUBMITTER: Varga T
PROVIDER: S-EPMC5142832 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Varga Tamas T Mounier Rémi R Patsalos Andreas A Gogolák Péter P Peloquin Matthew M Horvath Attila A Pap Attila A Daniel Bence B Nagy Gergely G Pintye Eva E Póliska Szilárd S Cuvellier Sylvain S Larbi Sabrina Ben SB Sansbury Brian E BE Spite Matthew M Brown Chester W CW Chazaud Bénédicte B Nagy Laszlo L
Immunity 20161108 5
Tissue regeneration requires inflammatory and reparatory activity of macrophages. Macrophages detect and eliminate the damaged tissue and subsequently promote regeneration. This dichotomy requires the switch of effector functions of macrophages coordinated with other cell types inside the injured tissue. The gene regulatory events supporting the sensory and effector functions of macrophages involved in tissue repair are not well understood. Here we show that the lipid activated transcription fac ...[more]