Ontology highlight
ABSTRACT:
SUBMITTER: Hartle MD
PROVIDER: S-EPMC5144539 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Hartle Matthew D MD Hansen Ryan J RJ Tresca Blakely W BW Prakel Samuel S SS Zakharov Lev N LN Haley Michael M MM Pluth Michael D MD Johnson Darren W DW
Angewandte Chemie (International ed. in English) 20160811 38
Hydrogen sulfide (H2 S) has emerged as a crucial biomolecule in physiology and cellular signaling. Key challenges associated with developing new chemical tools for understanding the biological roles of H2 S include developing platforms that enable reversible binding of this important biomolecule. The first synthetic small molecule receptor for the hydrosulfide anion, HS(-) , using only reversible, hydrogen-bonding interactions in a series of bis(ethynylaniline) derivatives, is reported. Binding ...[more]