Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae.
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ABSTRACT:
SUBMITTER: Riska PF
PROVIDER: S-EPMC514725 | biostudies-literature | 2004 Sep
REPOSITORIES: biostudies-literature
Publications
Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae.
Riska Paul F PF Kutlin Andrei A Ajiboye Patrick P Cua Arnold A Roblin Patricia M PM Hammerschlag Margaret R MR
Antimicrobial agents and chemotherapy 20040901 9
Three clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C. pneumoniae isolates. No macrolide resistance was obtained in vitro. ...[more]
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