Ontology highlight
ABSTRACT:
SUBMITTER: Jumar A
PROVIDER: S-EPMC5147800 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Jumar Agnes A Harazny Joanna M JM Ott Christian C Friedrich Stefanie S Kistner Iris I Striepe Kristina K Schmieder Roland E RE
PloS one 20161209 12
<h4>Purpose</h4>In diabetes mellitus type 2, capillary rarefaction plays a pivotal role in the pathogenesis of end-organ damage. We investigated retinal capillary density in patients with early disease.<h4>Methods</h4>This cross-sectional study compares retinal capillary rarefaction determined by intercapillary distance (ICD) and capillary area (CapA), measured non-invasively and in vivo by scanning laser Doppler flowmetry, in 73 patients with type 2 diabetes, 55 healthy controls and 134 individ ...[more]