Ontology highlight
ABSTRACT:
SUBMITTER: Jaatinen ST
PROVIDER: S-EPMC514979 | biostudies-literature | 2004 Sep
REPOSITORIES: biostudies-literature
Jaatinen Silja T ST Viitanen Salla J SJ Bamford Dennis H DH Bamford Jaana K H JK
Journal of virology 20040901 18
The icosahedral membrane-containing double-stranded DNA bacteriophage PRD1 has a labile receptor binding spike complex at the vertices. This complex, which is analogous to that of adenovirus, is formed of the penton protein P31, the spike protein P5, and the receptor binding protein P2. Upon infection, the internal phage membrane transforms into a tubular structure that protrudes through a vertex and penetrates the cell envelope for DNA injection. We describe here a new class of PRD1 mutants lac ...[more]