Ontology highlight
ABSTRACT:
SUBMITTER: Honda T
PROVIDER: S-EPMC5150256 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Honda Takuya T Soeda Shuhei S Tsuda Kunihiko K Yamaguchi Chihiro C Aoyama Kazumasa K Morinaga Takao T Yuki Ryuzaburo R Nakayama Yuji Y Yamaguchi Noritaka N Yamaguchi Naoto N
Scientific reports 20161212
Src-family tyrosine kinases, which are expressed in various cell types, play critical roles in cell signalling at the cytoplasmic side of the plasma membrane through their lipid modifications. Src-family kinases are cotranslationally myristoylated and posttranslationally palmitoylated in the amino-terminal region. The Src-family member Lyn contains a myristoylation site at glycine-2 and a palmitoylation site at cysteine-3, whereas c-Src has a myristoylation site at glycine-2 but not any palmitoy ...[more]