Ontology highlight
ABSTRACT:
SUBMITTER: Collantes J
PROVIDER: S-EPMC5154436 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Collantes Jimena J Solari Francesca Barletta FB Rigouts Leen L
The American journal of tropical medicine and hygiene 20161024 6
Drug susceptibility testing using molecular techniques can enhance the identification of drug-resistant Mycobacterium tuberculosis Two multiplex real-time polymerase chain reaction (qPCR) assays were developed to detect the most common resistance-associated mutations to isoniazid (katGS315T, inhA-15C → T), and rifampicin (rpoBH526Y and rpoBS531L). To assess the species specificity of the qPCR, we selected 31 nontuberculous mycobacteria (NTM) reference strains belonging to 17 species from the pub ...[more]