MLST-based inference of genetic diversity and population structure of clinical Klebsiella pneumoniae, China.
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ABSTRACT:
SUBMITTER: Guo C
PROVIDER: S-EPMC5154592 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Publications
MLST-based inference of genetic diversity and population structure of clinical Klebsiella pneumoniae, China.
Guo Chenyi C Yang Xianwei X Wu Yarong Y Yang Huiying H Han Yanping Y Yang Ruifu R Hu Liangping L Cui Yujun Y Zhou Dongsheng D
Scientific reports 20150105
Multilocus sequence typing was applied to a collection of 327 clinical isolates of Klebsiella pneumoniae from China, which was proven to be a good representative of the global diversity of K. pneumoniae. Three lineages L1 to L3 are presented in the population with limited genetic flow across different lineages. However, extremely high levels of recombination can be observed within lineages to the extent at which the alleles are associated almost randomly. Lineages L2 and L3 most likely represent ...[more]
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