Simultaneous edited MRS of GABA and glutathione.
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ABSTRACT:
SUBMITTER: Saleh MG
PROVIDER: S-EPMC5159266 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
Simultaneous edited MRS of GABA and glutathione.
Saleh Muhammad G MG Oeltzschner Georg G Chan Kimberly L KL Puts Nicolaas A J NAJ Mikkelsen Mark M Schär Michael M Harris Ashley D AD Edden Richard A E RAE
NeuroImage 20160814
Edited MRS allows the detection of low-concentration metabolites, whose signals are not resolved in the MR spectrum. Tailored acquisitions can be designed to detect, for example, the inhibitory neurotransmitter γ-aminobutyric acid (GABA), or the reduction-oxidation (redox) compound glutathione (GSH), and single-voxel edited experiments are generally acquired at a rate of one metabolite-per-experiment. We demonstrate that simultaneous detection of the overlapping signals of GABA and GSH is possib ...[more]
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