Ontology highlight
ABSTRACT:
SUBMITTER: Gentry MS
PROVIDER: S-EPMC5161650 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Current opinion in structural biology 20160804
Glucan phosphatases are functionally conserved at the enzymatic level, dephosphorylating glycogen in animals and starch in plants. The human glucan phosphatase laforin is the founding member of the family and it is comprised of a carbohydrate binding module (CBM) domain followed by a dual specificity phosphatase (DSP) domain. Plants encode two glucan phosphatases: Starch EXcess4 (SEX4) and Like Sex Four2 (LSF2). SEX4 contains a DSP domain followed by a CBM domain, while LSF2 contains a DSP domai ...[more]