Molecular Evolution of the Glycosyltransferase 6 Gene Family in Primates.
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ABSTRACT:
SUBMITTER: Evanovich E
PROVIDER: S-EPMC5164903 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Molecular Evolution of the Glycosyltransferase 6 Gene Family in Primates.
Evanovich Eliane E Mendonça-Mattos Patricia Jeanne de Souza PJ Harada Maria Lúcia ML
Biochemistry research international 20161204
Glycosyltransferase 6 gene family includes ABO, Ggta1, iGb3S, and GBGT1 genes and by three putative genes restricted to mammals, GT6m6, GTm6, and GT6m7, only the latter is found in primates. GT6 genes may encode functional and nonfunctional proteins. Ggta1 and GBGT1 genes, for instance, are pseudogenes in catarrhine primates, while iGb3S gene is only inactive in human, bonobo, and chimpanzee. Even inactivated, these genes tend to be conversed in primates. As some of the GT6 genes are related to ...[more]
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