Ontology highlight
ABSTRACT:
SUBMITTER: McAndrew RP
PROVIDER: S-EPMC5167157 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
McAndrew Ryan P RP Sathitsuksanoh Noppadon N Mbughuni Michael M MM Heins Richard A RA Pereira Jose H JH George Anthe A Sale Kenneth L KL Fox Brian G BG Simmons Blake A BA Adams Paul D PD
Proceedings of the National Academy of Sciences of the United States of America 20161130 50
Stilbenes are diphenyl ethene compounds produced naturally in a wide variety of plant species and some bacteria. Stilbenes are also derived from lignin during kraft pulping. Stilbene cleavage oxygenases (SCOs) cleave the central double bond of stilbenes, forming two phenolic aldehydes. Here, we report the structure of an SCO. The X-ray structure of NOV1 from Novosphingobium aromaticivorans was determined in complex with its substrate resveratrol (1.89 Å), its product vanillin (1.75 Å), and witho ...[more]