Ontology highlight
ABSTRACT:
SUBMITTER: Svagan AJ
PROVIDER: S-EPMC5167381 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
PloS one 20161219 12
Drug targeting to the colon via the oral administration route for local treatment of e.g. inflammatory bowel disease and colonic cancer has several advantages such as needle-free administration and low infection risk. A new source for delivery is plant-polysaccharide based delivery platforms such as Rhamnogalacturonan-I (RG-I). In the gastro-intestinal tract the RG-I is only degraded by the action of the colonic microflora. For assessment of potential drug delivery properties, RG-I based microca ...[more]