Ontology highlight
ABSTRACT:
SUBMITTER: Vargas T
PROVIDER: S-EPMC5167383 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Vargas Teodoro T Moreno-Rubio Juan J Herranz Jesús J Cejas Paloma P Molina Susana S Mendiola Marta M Burgos Emilio E Custodio Ana B AB De Miguel María M Martín-Hernández Roberto R Reglero Guillermo G Feliu Jaime J Ramírez de Molina Ana A
PloS one 20161219 12
Strong evidence suggests that lipid metabolism (LM) has an essential role in tumor growth to support special energetic and structural requirements of tumor cells. Recently, overexpression of LM-related genes, apolipoproteins related to metabolic syndrome, and ACSL/SCD network involved in fatty acid activation have been proposed as prognostic markers of colon cancer (CC). Furthermore, activation of this latter lipid network has been recently demonstrated to confer invasive and stem cell propertie ...[more]