Ontology highlight
ABSTRACT:
SUBMITTER: Chavez JD
PROVIDER: S-EPMC5172568 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Chavez Juan D JD Eng Jimmy K JK Schweppe Devin K DK Cilia Michelle M Rivera Keith K Zhong Xuefei X Wu Xia X Allen Terrence T Khurgel Moshe M Kumar Akhilesh A Lampropoulos Athanasios A Larsson Mårten M Maity Shuvadeep S Morozov Yaroslav Y Pathmasiri Wimal W Perez-Neut Mathew M Pineyro-Ruiz Coriness C Polina Elizabeth E Post Stephanie S Rider Mark M Tokmina-Roszyk Dorota D Tyson Katherine K Vieira Parrine Sant'Ana Debora D Bruce James E JE
PloS one 20161220 12
Chemical cross-linking mass spectrometry (XL-MS) provides protein structural information by identifying covalently linked proximal amino acid residues on protein surfaces. The information gained by this technique is complementary to other structural biology methods such as x-ray crystallography, NMR and cryo-electron microscopy[1]. The extension of traditional quantitative proteomics methods with chemical cross-linking can provide information on the structural dynamics of protein structures and ...[more]