Ontology highlight
ABSTRACT:
SUBMITTER: Xu JH
PROVIDER: S-EPMC5173237 | biostudies-literature | 2005 Nov
REPOSITORIES: biostudies-literature
Genomics, proteomics & bioinformatics 20051101 4
G-protein coupled receptors (GPCRs) are a class of seven-helix transmembrane proteins that have been used in bioinformatics as the targets to facilitate drug discovery for human diseases. Although thousands of GPCR sequences have been collected, the ligand specificity of many GPCRs are still unknown and only one crystal structure of the rhodopsin-like family has been solved. Therefore, identifying GPCR types only from sequence data has become an important research issue. In this study, a novel t ...[more]