Ontology highlight
ABSTRACT:
SUBMITTER: Kupitz C
PROVIDER: S-EPMC5178802 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Structural dynamics (Melville, N.Y.) 20161215 4
Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals are mixed with a substrate just prior to being probed by an X-ray pulse. This approach offers several advantages over flow cell studies. It provides (i) room temperature structures at near atomic resolution, (ii) time resolution ranging from microseconds to seconds, and (iii) convenient reaction initiation. It outruns radiation damage by using femtosecond X-ray ...[more]