Ontology highlight
ABSTRACT:
SUBMITTER: Zeth K
PROVIDER: S-EPMC518833 | biostudies-literature | 2004 Sep
REPOSITORIES: biostudies-literature
Zeth Kornelius K Offermann Stefanie S Essen Lars-Oliver LO Oesterhelt Dieter D
Proceedings of the National Academy of Sciences of the United States of America 20040913 38
The crystal structure of the Dps-like (Dps, DNA-protecting protein during starvation) ferritin protein DpsA from the halophile Halobacterium salinarum was determined with low endogenous iron content at 1.6-A resolution. The mechanism of iron uptake and storage was analyzed in this noncanonical ferritin by three high-resolution structures at successively increasing iron contents. In the high-iron state of the DpsA protein, up to 110 iron atoms were localized in the dodecameric protein complex. Fo ...[more]