Ontology highlight
ABSTRACT:
SUBMITTER: Zhao H
PROVIDER: S-EPMC5190068 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Zhao Haiyue H Guo Ensong E Hu Ting T Sun Qian Q Wu Jianli J Lin Xingguang X Luo Danfeng D Sun Chaoyang C Wang Changyu C Zhou Bo B Li Na N Xia Meng M Lu Hao H Meng Li L Xu Xiaoyan X Hu Junbo J Ma Ding D Chen Gang G Zhu Tao T
Oncotarget 20160701 28
Approximately 50-75% of patients with serous ovarian carcinoma (SOC) experience recurrence within 18 months after first-line treatment. Current clinical indicators are inadequate for predicting the risk of recurrence. In this study, we used 7 publicly available microarray datasets to identify gene signatures related to recurrence in optimally debulked SOC patients, and validated their expressions in an independent clinic cohort of 127 patients using immunohistochemistry (IHC). We identified a tw ...[more]