Ontology highlight
ABSTRACT:
SUBMITTER: Abreu AP
PROVIDER: S-EPMC5192018 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Abreu Ana Paula AP Kaiser Ursula B UB
The lancet. Diabetes & endocrinology 20160204 3
Puberty marks the end of childhood and is a period when individuals undergo physiological and psychological changes to achieve sexual maturation and fertility. The hypothalamic-pituitary-gonadal axis controls puberty and reproduction and is tightly regulated by a complex network of excitatory and inhibitory factors. This axis is active in the embryonic and early postnatal stages of life and is subsequently restrained during childhood, and its reactivation culminates in puberty initiation. The me ...[more]