Ontology highlight
ABSTRACT:
SUBMITTER: Vallacchi V
PROVIDER: S-EPMC5192500 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Vallacchi Viviana V Camisaschi Chiara C Dugo Matteo M Vergani Elisabetta E Deho Paola P Gualeni Ambra A Huber Veronica V Gloghini Annunziata A Maurichi Andrea A Santinami Mario M Sensi Marialuisa M Castelli Chiara C Rivoltini Licia L Rodolfo Monica M
Genes 20161214 12
Sentinel node biopsy (SNB) is a main staging biomarker in melanoma and is the first lymph node to drain the tumor, thus representing the immunological site where anti-tumor immune dysfunction is established and where potential prognostic immune markers can be identified. Here we analyzed microRNA (miR) profiles in archival tumor-positive SNBs derived from melanoma patients with different outcomes and performed an integrated analysis of transcriptional data to identify deregulated immune signalin ...[more]