Ontology highlight
ABSTRACT:
SUBMITTER: Menefee DS
PROVIDER: S-EPMC7803563 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Menefee Derek S DS McMasters Austin A Pan Jianmin J Li Xiaohong X Xiao Deyi D Waigel Sabine S Zacharias Wolfgang W Rai Shesh N SN McMasters Kelly M KM Hao Hongying H
Aging 20201229 24
Age is an important factor for determining the outcome of melanoma patients. Sentinel lymph node (SLN) status is also a strong predictor of survival for melanoma. Paradoxically, older melanoma patients have a lower incidence of SLN metastasis but a higher mortality rate when compared with their younger counterparts. The mechanisms that underlie this phenomenon remain unknown. This study uses three independent datasets of RNA samples from patients with melanoma metastatic to the SLN to identify a ...[more]