Ontology highlight
ABSTRACT:
SUBMITTER: Sala FA
PROVIDER: S-EPMC5192694 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Biophysical journal 20161201 12
Protein-protein interactions play a critical role in promoting the stability of protein quaternary structure and in the assembly of large macromolecular complexes. What drives the stabilization of such assemblies is a central question in biology. A limiting factor in fully understanding such systems is the transient nature of many complexes, making structural studies difficult. Septins comprise a conserved family of guanine nucleotide binding proteins that polymerize in the form of heterofilamen ...[more]