Ontology highlight
ABSTRACT:
SUBMITTER: Knight KM
PROVIDER: S-EPMC5201171 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Knight Katrina M KM Moalli Pamela A PA Nolfi Alexis A Palcsey Stacy S Barone William R WR Abramowitch Steven D SD
International urogynecology journal 20160212 8
<h4>Introduction and hypothesis</h4>Parity is the leading risk factor for the development of pelvic organ prolapse. To assess the impact of pregnancy and delivery on vaginal tissue, researchers commonly use nonhuman primate (NHP) and rodent models. The purpose of this study was to evaluate the ewe as an alternative model by investigating the impact of parity on the ewe vaginal mechanical properties and collagen structure.<h4>Methods</h4>Mechanical properties of 15 nulliparous and parous ewe vagi ...[more]