Progress toward active or passive HIV-1 vaccination.
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ABSTRACT:
SUBMITTER: Escolano A
PROVIDER: S-EPMC5206506 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Publications
Progress toward active or passive HIV-1 vaccination.
Escolano Amelia A Dosenovic Pia P Nussenzweig Michel C MC
The Journal of experimental medicine 20161221 1
AIDS is a preventable disease. Nevertheless, according to UNAIDS, 2.1 million individuals were infected with HIV-1 in 2015 worldwide. An effective vaccine is highly desirable. Most vaccines in clinical use today prevent infection because they elicit antibodies that block pathogen entry. Consistent with this general rule, studies in experimental animals have shown that broadly neutralizing antibodies to HIV-1 can prevent infection, suggesting that a vaccine that elicits such antibodies would be p ...[more]
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