PD-1/PD-L1 inhibitors in multiple myeloma: The present and the future.
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ABSTRACT:
SUBMITTER: Jelinek T
PROVIDER: S-EPMC5215080 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
PD-1/PD-L1 inhibitors in multiple myeloma: The present and the future.
Oncoimmunology 20161108 12
The introduction of PD-1/PD-L1 pathway inhibitors has marked a significant milestone in the treatment of various types of solid tumors. The current situation in multiple myeloma (MM) is rather unclear, as distinct research groups have reported discordant results. This discrepancy dominantly concerns the expression of PD-1/PD-L1 molecules as well as the identification of the responsible immune effector cell population. The results of monotherapy with PD-1/PD-L1 inhibitors have been unsatisfactory ...[more]
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