Ontology highlight
ABSTRACT:
SUBMITTER: Kuwahara T
PROVIDER: S-EPMC522005 | biostudies-literature | 2004 Oct
REPOSITORIES: biostudies-literature
Kuwahara Tomomi T Yamashita Atsushi A Hirakawa Hideki H Nakayama Haruyuki H Toh Hidehiro H Okada Natsumi N Kuhara Satoru S Hattori Masahira M Hayashi Tetsuya T Ohnishi Yoshinari Y
Proceedings of the National Academy of Sciences of the United States of America 20041004 41
Bacteroides are predominant human colonic commensals, but the principal pathogenic species, Bacteroides fragilis (BF), lives closely associated with the mucosal surface, whereas a second major species, Bacteroides thetaiotaomicron (BT), concentrates within the colon. We find corresponding differences in their genomes, based on determination of the genome sequence of BF and comparative analysis with BT. Both species have acquired two mechanisms that contribute to their dominance among the colonic ...[more]