Ontology highlight
ABSTRACT:
SUBMITTER: Liu S
PROVIDER: S-EPMC5225015 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Liu Sheng S Gao Wenjie W Wang Yao Y He Zhenyu Z Feng Xiaojun X Liu Bi-Feng BF Liu Xin X
PloS one 20170110 1
Monitoring glycosylation of the mAbs have been emphasized and routinely characterized in biopharmaceutical industries because the carbohydrate components are closely related to the safety, efficacy, and consistency of the antibodies. In this study, the comprehensive glycan profiling of a biosimilar candidate of cetuximab was successfully characterized using Normal phase high-performance liquid chromatography (NP-HPLC) in combination with Matrix assisted laser desorption/ionization mass spectrome ...[more]