Ontology highlight
ABSTRACT:
SUBMITTER: Gilgunn S
PROVIDER: S-EPMC4961449 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Gilgunn Sarah S Millán Martín Silvia S Wormald Mark R MR Zapatero-Rodríguez Julia J Conroy Paul J PJ O'Kennedy Richard J RJ Rudd Pauline M PM Saldova Radka R
PloS one 20160726 7
Recent exploitation of the avian immune system has highlighted its suitability for the generation of high-quality, high-affinity antibodies to a wide range of antigens for a number of therapeutic and biotechnological applications. The glycosylation profile of potential immunoglobulin therapeutics is species specific and is heavily influenced by the cell-line/culture conditions used for production. Hence, knowledge of the carbohydrate moieties present on immunoglobulins is essential as certain gl ...[more]