Ontology highlight
ABSTRACT:
SUBMITTER: Jacobson O
PROVIDER: S-EPMC5226408 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Jacobson Orit O Yan Xuefeng X Niu Gang G Weiss Ido D ID Ma Ying Y Szajek Lawrence P LP Shen Baozhong B Kiesewetter Dale O DO Chen Xiaoyuan X
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20150219 4
<h4>Unlabelled</h4>Tenascin-C is an extracellular matrix glycoprotein that is expressed by injured tissues and by various cancers. Recent publications showed that tenascin-C expression by cancer lesions predicts tumor growth, metastasis, and angiogenesis, suggesting tenascin-C as a potential therapeutic target. Currently there is no noninvasive method to determine tumoral tenascin-C expression in vivo. To address the need for an agent to image and quantify tenascin-C, we report the development o ...[more]