Ontology highlight
ABSTRACT:
SUBMITTER: Silva TA
PROVIDER: S-EPMC5226564 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Silva Thaiomara A TA Smuczek Basílio B Valadão Iuri C IC Dzik Luciana M LM Iglesia Rebeca P RP Cruz Mário C MC Zelanis André A de Siqueira Adriane S AS Serrano Solange M T SM Goldberg Gary S GS Jaeger Ruy G RG Freitas Vanessa M VM
Oncotarget 20160801 31
Extracellular vesicles play important roles in tumor development. Many components of these structures, including microvesicles and exosomes, have been defined. However, mechanisms by which extracellular vesicles affect tumor progression are not fully understood. Here, we investigated vesicular communication between mammary carcinoma cells and neighboring nontransformed mammary fibroblasts. Nonbiased proteomic analysis found that over 1% of the entire proteome is represented in these vesicles, wi ...[more]