Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC5227651 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Wang Shouju S Teng Zhaogang Z Huang Peng P Liu Dingbin D Liu Ying Y Tian Ying Y Sun Jing J Li Yanjun Y Ju Huangxian H Chen Xiaoyuan X Lu Guangming G
Small (Weinheim an der Bergstrasse, Germany) 20150107 15
Shielding nanoparticles from nonspecific interactions with normal cells/tissues before they reach and after they leave tumors is crucial for the selective delivery of NPs into tumor cells. By utilizing the reversible protonation of weak electrolytic groups to pH changes, long-chain amine/carboxyl-terminated polyethylene glycol (PEG) decorated gold nanostars (GNSs) are designed, exhibiting reversible, significant, and sensitive response in cell affinity and therapeutic efficacy to the extracellul ...[more]