Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC5233986 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Wang Long L Zhou Mai-Tao MT Chen Cai-Yang CY Yin Wen W Wen Da-Xiang DX Cheung Chi-Wai CW Yang Li-Qun LQ Yu Wei-Feng WF
Scientific reports 20170113
Requirement for rocuronium upon surgery changes only minimally in patients with end-stage liver diseases. Our study consisted of both human and rat studies to explore the reason. The reduction rate of rocuronium infusion required to maintain neuromuscular blockade during the anhepatic phase (relative to paleohepatic phase) was examined in 16 children with congenital biliary atresia receiving orthotopic liver transplantation. Pharmacodynamics and pharmacokinetics of rocuronium were studied based ...[more]