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Direct arylation catalysis with chloro[8-(dimesitylboryl)quinoline-?N]copper(I).

ABSTRACT: We report direct arylation of arylhalides with unactivated sp² C-H bonds in benzene and naphthalene using a copper(I) catalyst featuring an ambiphilic ligand, (quinolin-8-yl)dimesitylborane. Direct arylation could be achieved with 0.2 mol % catalyst and 3 equivalents of base (KO(t-Bu)) at 80 °C to afford TON ?160-190 over 40 hours.

SUBMITTER: Tamang SR

PROVIDER: S-EPMC5238606 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Direct arylation catalysis with chloro[8-(dimesitylboryl)quinoline-κN]copper(I).

Tamang Sem Raj SR Hoefelmeyer James D JD

Beilstein journal of organic chemistry 20161215

We report direct arylation of arylhalides with unactivated sp<sup>2</sup> C-H bonds in benzene and naphthalene using a copper(I) catalyst featuring an ambiphilic ligand, (quinolin-8-yl)dimesitylborane. Direct arylation could be achieved with 0.2 mol % catalyst and 3 equivalents of base (KO(<i>t</i>-Bu)) at 80 °C to afford TON ≈160-190 over 40 hours. ...[more]

PMID: 28144346

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