Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC5244253 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Wang Jianfeng J Liu Bowen B Teng Zihao Z Zhou Xuan X Wang Xiyan X Zhang Bing B Lu Gejin G Niu Xiaodi X Yang Yongjun Y Deng Xuming X
Frontiers in cellular and infection microbiology 20170119
The critical roles of sortase A (SrtA) and listeriolysin O (LLO) in <i>Listeria monocytogenes</i> pathogenicity render these two virulence factors as ideal targets for the development of anti-virulence agents against <i>L. monocytogenes</i> infection. Additionally, the structures of SrtA and LLO are highly conserved among the members of sortase enzyme family and cholesterol dependent toxin family. Here, phloretin, a natural polyphenolic compound derived from apples and pears that has little anti ...[more]